National clinical stroke guidelines issued by the Royal College of Physicians (RCP) recommends all patients, regardless of age or severity of stroke, should be considered for thrombolysis.
Research from the RCP's intercollegiate stroke working party a found these categories of patient, formerly not thought to benefit from thrombolysis, should be offered it with other patients within three hours of the appearance of stroke symptoms.
The recommendation is one of several updates to blueprint for stroke care across England and Wales, which includes more than 100 sources of evidence of developments in stroke research over the past four years and embeds NICE quality standards and guidelines.